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Varane was subbed off at half-time of United’s comeback win over Nottingham Forest on Saturday, and replaced by Victor Lindelof.
After poor performances in their opening games against Wolves and Tottenham,it appeared the Red Devils were still on the beach as they went 2-0 down within four minutes at Old Trafford.
They rallied after that, with Christian Eriksen pulling one back before the break, before Casemiro levelled the score in the 52nd minute and Bruno Fernandes completed the turnaround with a late penalty after Forest went down to 10 men.
Up next, United take on rivals Arsenal who remain unbeaten after three games though could only disappointingly draw 2-2 at home to 10-man Fulham on Saturday.
But they could be without key defender Varane who has been struggling with fitness issues since before the campaign began, with his early withdrawal against Forest worrying fans.
Asked about how the French centre-back was, Ten Hag said post-match: ‘He had complaints, we didn’t want to risk him.
‘We have Harry Maguire, Victor Lindelof, who could replace him, so we don’t take a risk.
‘He had complaints and if it’s really bad I don’t know, we have to wait.’
If Varane injury’s is bad, he’ll join a growing list of player’s in United’s treatment room, that now includes Rasmus Hojlund and Mason Mount.
Moreover, both Luke Shaw and Tyrell Malacia are both on the sidelines meaning right-back Diogo Dalot was forced to start at left-back, with the England international expected to be out injured until November.
As a result, United are looking to sign free agent and former Chelsea, Southampton and Leicester defender Ryan Bertrand.
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